Very good job on this, i really like the line art, your work is allmost spot on really. Its a very clean and cool piece of lineart. I think this will look pretty good when finished, what kind of scene are you trying to show?
Id say you where simply over thinking the hands and trousers, as in you though you needed to put lots of detail into the wrinkles, well you dont. You may feel you have to, but a wierd wrinkly mess can ruin a picture. To be honest at the line art stage you hardly have to worry about wrinkles, its best do them in the colouring stage.
The only thing you have to think about really with trousers is that theyre being pulled down, quite like a curtain, at the bottom the weight causes them to crumple. Because you character is female Id think her trousers would be quite tight, so position the trousers quite snugly around the thy.
Just think they go down. Unless theyre being directly pulled by somthing (wasit, knee, hand, car?).
I dont think the wrinkles in the knees would happen in real life, maybe though, but not as dominante as theyre shown.